Liquid-based cytology (LBC) combined with reflex detection of HR-HPV types in cases of minor cytological abnormalities probably provides increased sensitivity and increased specificity for the detection of high-grade cervical lesions, when used in population-based screening.
By merging the raw junctions and then setting the cutoff according to the overall exon coverage, we are aiming at improving sensitivity for shared junctions and to increase specificity for the sample-specific junctions.
In contrast, tumor cells and tumor DNA found in the lungs are most likely from lung tumors or lung metastases and therefore lead to an increased specificity for lung cancer due to the choice of a lung specific analyte.
In addition, the V148W, V148L, A200I, and V148L/A200I variants had increased specificity for catechol.
Wild-type CotA oxidizes ABTS ABTSS = diammonium 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonate 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonate 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonate 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonate 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonate 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonate
As expected, adjustment for verification bias decreased sensitivity and increased specificity for all tests.
DHE has increased specificity for superoxide compared with other dyes which are more general reactive oxygen species probes.
The combination of the hyaluronidase digestion with a subsequent alcian blue stain increased specificity for various acid mucosubstances in the alcian blue stain.
Furthermore, spiperone, which was used as the radioligand in [34] recognizes D2R and D4R to a similar extent (Ki 0.06 nM and 0.08 nM respectively) but also has affinity at 5-HT receptors, while raclopride (used in this study) shows increased specificity for D2Rs over D3Rs and D4Rs (Ki 1.8 nM, 3.5 nM and 2400 nM respectively), and little affinity at 5-HT receptors.
