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Ever since Liang et al (1999) reported that the presence of CDKN2A promoter hypermethylation predicted shorter survival in colorectal cancer patients, the prognostic value of CDKN2A hypermethylation in colorectal cancer have been widely investigated, owing to the fact that these results exhibited an increasing relevance with clinical practice.
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Health, educational and quality of life (QoL) outcomes have increasing relevance to children with serious congenital heart defects (CHDs), who can now expect to survive into adulthood.
An area of application of measurement with increasing relevance to science and society is interdisciplinary research.
Model-driven development is a generative software development process with increasing relevance both in industry and academia.
A Misunderstood Friendship adds new depth to our understanding of one of the most secretive and significant relationships of the Cold War, with increasing relevance to international affairs today.
The dynamics of deformable liquid-filled bodies (e.g., droplets, capsules, lipid vesicles) suspended in a fluid flow is a fascinating fundamental problem with increasing relevance for technological applications, for example, in drug delivery, or designing lab-on-chip devices.
The default-mode network (DMN) is a functional network with increasing relevance for psychiatric research, characterized by increased activation at rest and decreased activation during task performance.
Given that the blandness of modern capitalism (depicted brilliantly in American Psycho) involves rendering art into mass entertainment and crass escapism, with the novel now dominated by formulaic genre fiction slotting into marketing holes and peddling easy resolution, Easton Ellis produced a groundbreaking work, with an increasing relevance to the world we live in.
Model results reveal a multi-dimensional dependence of the investigated variables with an increasing relevance of the sea-side boundary slope for seawater intrusion (decrease of up to 32%), submarine groundwater discharge zone (reduction of up to 55%), and turnover times (increase of up to 730%) with increasing freshwater inflow or dispersivity values.
The toxicity of ART is a question of increasing relevance in the treatment of patients with HIV infection due to the need of maintaining ART indefinitely in order to achieve clinical benefits.
Procurement overheads, on which we could not find any evidence, are nevertheless likely to be of increasing relevance to programme planners and evaluations with repeated bed net purchasing and distribution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com