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In recent years, tens of thousands of single protein structures have been solved using these methods, as well as an increasing number of complexes.
These results suggest that for proteins participating in increasing number of complexes, lower dN/dS ratios tend to be associated with purifying selection to maintain organism fitness.
However, we found that the distribution of essential genes across complexes is not significantly different from that of inessential genes (p-value = 0.34, one-sided Fisher's exact test), with both distributions showing an exponential decay in the fraction of genes with increasing number of complexes in which they are present (Fig. 2).
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The reasons for the shortage include an aging population, more people working away from their offices and the increasing number of complex, blood-demanding procedures being performed, she said.
He said a recent survey had found that 77% of judges with leadership responsibilities felt their work had increased significantly in the past three years, and that they were having to deal with an increasing number of complex matters in addition to their daily court sittings.
Future automobiles will support an increasing number of complex, distributed functions such as active safety and X-by-wire.
Cancer nurses are also tasked with delivering an increasing number of complex interventions as a result of on-going clinical trials in cancer research.
While genome-wide association studies in humans and quantitative trait loci (QTL) analyses in mice have identified candidate genes for an increasing number of complex traits and genetic diseases, the resources and time-consuming process necessary for obtaining detailed quantitative data have made sleep seemingly intractable to similar large-scale genomic approaches.
This has resulted in an increasing number of complex intervention studies commencing in Australian general practice over the past five years.
Emergency response cannot overshadow development aid The increasing number of complex emergencies creates the potential for acute crises to overshadow development work.
The autoinflammatory family now includes an increasing number of complex, polygenic/multifactorial diseases (including PFAPA, adult onset Still's disease, chronic recurrent multifocal osteomyelitis, Behçet's and Crohn's disease) that are of unknown etiology.
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CEO of Professional Science Editing for Scientists @ prosciediting.com