While NGS assays will undoubtedly increase novel allele identification, more stringent DNA sample requirements may be necessary for this new technology.
Therefore, searching high quality unassigned mass spectra against translated novel junction sequences would be beneficial on both sides: increasing the novel junction identifications, and increasing the number of spectra assignments.
Drug-resistant malaria is increasing, and novel strategies to monitor for resistance are needed.
Awareness of rickettsiae as causes of public health problems has been increasing; several novel or emerging diseases caused by these pathogens have been recognized.
As the number of people suffering from pain keeps increasing, few novel molecular entities to fight pain have entered the clinic in the past 50 years, despite the increasing pharmaceutical investment (Woodcock et al., 2007; Melzack, 2008; Kissin, 2010).
Furthermore, should transmitted NNRTI resistance increase, novel, less cross-resistant compounds would be needed even in early lines of therapy.
It is observed that larger slug size increases the novel foam gas injection rate and enlarges the contrast between two types of foams (Fig. 27) since the novel foam will lower the injection pressure further with larger slug size.
Mr. Prokhanov's offbeat personality has increased the novel's mystique.
So, unexpectedly, is US president Calvin Coolidge, whose name is invoked in the last page of the notes to label a well-known sexual phenomenon: that lustful enthusiasm in a male tends to increase with novel females.
The political and cultural ascendancy of the middle class increased the novel's popularity and prestige, giving rise in the 19th century to the predicament in which Mr. Franzen currently finds himself.
