Sentence examples for increasing mutations that from inspiring English sources

We identified a number of strong, monotonically increasing mutations that formed a particularly distinct cluster (Figure 4C).

Therefore, we conclude that the most likely explanation for the high levels of divergence is an increased mutation rate that is specific to atp9 (or a subset of the mitochondrial genome that includes atp9).

One hypothesis that may explain an accelerated chromosomal evolution rate is an increased mutation rate that generates more rearrangements per generation.

Agonist-unbound GPCRs usually show basal activity that is enhanced by agonist binding, reduced by inverse agonist binding, unaffected by neutral antagonists and increased by mutations that lead to constitutively active mutants (CAMs).

While the importance of individual genetic makeup (intrinsic factors) in longevity and delayed onset of diseases is logical, how the confounding extrinsic factors such as the interactions of oxidative stress and aging process would lead to increased somatic mutations that affect the regulations of biological clocks and functions of organ systems in the direction of diseases are not understood.

We have demonstrated that CYP21A2 is a progesterone 16α-hydroxylase, which is markedly increased with mutations that reduce the bulk of V359.

Similarly, the translational level of an enzyme can be increased by mutations that alter codon usage efficiency, mRNA stability, or ribosome binding strength.

Contaminant exposure can lead to an increased mutation rate that might offset some of the genetic diversity loss caused by bottlenecks.

It is possible that the observed increased mutation frequencies that we observed in these same sub-structures of the mouse during aging are solely due to increased oxidative stress.

This is generally attributed to an increased mutation rate that continually produces new genetically defined clonal lineages.

Clones can acquire both advantageous and deleterious mutations, and mutator mutations that increase a cell's intrinsic mutation rate.