Exact(60)
Increasing marker duration did not produce an overestimation of the empty time intervals.
Therefore, we suggest the QTLs identified in the present study may be further reconfirmed by increasing marker density and size of the association panel.
In general, increasing marker density can increase the resolution of the genetic map, thus enhancing the precision of QTL mapping.
Second, having identified increases in the variance of each of these measures with increasing marker number, we apply a normalising transformation to make our heterozygosity data statistically comparable.
The observed fluctuations of sample points around the representative points may also reflect effects from subtle population structure and cannot be reduced by increasing marker numbers.
Increasing marker density ten times to 4,800,000 may not increase power significantly since the mean r2 only increases to 0.207 (median r2 = 0.096).
As our ultimate goal here was to pinpoint the causal variant of NRG1, increasing marker density outweighed the use of the less dense yet more accurate Phase III panel.
Rice cultivars within each varietal group are differentiated genetically across a host of molecular marker types including isozymes [4], [5], RFLPs [6], [7], SSRs [8], [9], SNPs [10] [12] and Tranposon Insertion Polymorphisms [13] with increasing resolution of population structure with increasing marker density and informativeness.
The accuracy increased with increasing marker density.
This bias disproportionally decreased with increasing marker density [ 45].
For all three methods, r2 decreased with increasing marker distance.
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