Sentence examples for increasing fragile from inspiring English sources

In vitro hypoxia exposure can also mediate larger scale genomic instability by increasing fragile site induction, gene amplification and cellular DNA content [ 7- 9].

With ever increasing fragile situations in the world, there is a push to identify effective tactics and responses to address the needs of the young in a crisis.

This is in agreement with our previous results showing that down-regulation of DNA-PKcs or Ligase IV by RNAi increased fragile site instability only under replication stress [15].

Furthermore, they found that down-regulation of RAD51 and DNA-PKcs increases fragile site instability, suggesting that both HR and NHEJ DSB repair pathways mediate break repair at fragile sites.

Studies have shown that a deficiency of proteins in the ATR-dependent cell cycle checkpoint pathway dramatically increases fragile site breakage [ 14].

This sex difference may indicate that increased fragile sites expression (genomic instability) is the results of enhanced OS associated with SCZ.

Furthermore, the drug aphidicolin, an inhibitor of polymerase α which by itself causes an increase in fragile telomeres (Sfeir et al., 2009), did not additionally increase the fragile and aberrant telomere phenotype of hStn1 knockdown cultures.

French banks increased their Fragile Five exposure by a modest 15% (to $69bn) – while chopping their Eurozone peripheral exposure by 43% to $514bn.

They work to increase the fragile standard of living for our people, but then one typhoon can set us back for years.

It is widely accepted that formula increases a fragile infant's risk of necrotizing enterocolitis -- the disease that claimed Micah's life.

Similar to normal BJ cells, aphidicolin did not significantly increase the fragile telomere phenotype due to hStn1 knockdown (Fig. S4C, Supporting information).