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Testing too early could be a factor increasing false negative results.
6, 8, 26 A higher possibility of lymph vascular invasion, lymph nodal involvement, and complete node replacement with tumor cells may hamper lymphatic flow, thus reducing detection rates and increasing false negative rates in larger tumors.
Authors hypothesize that this approach may allow identification of frequent and consistent epistatic effects at the expense of lower test power, improving the filtering of false positive results at the expense of increasing false negative rate.
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Employing strict significance thresholds when testing individual SNPs avoids false positives at the expense of increasing false negatives.
Spatial congruence between "true" and "estimated" hotspots declined rapidly with increasing time interval between surveys, due primarily to increasing false negatives (i.e., missing "true" hotspots).
HF1 was too stringent, and HF3/HF4 tended to either suffer from increasing false positives or increasing false negatives as the number of gene trees increased.
decreases false positives, there is a clear trade-off between decreasing false positives by eliminating low-quality bases and increasing false negatives by disregarding good data.
However, if copy number variants were important, we suggest that they would add noise to our current SNP-MaP screening, thus increasing false negatives rather than false positives.
This difference likely owes to the extra covariate (kinship matrix) that results in the MLM test avoiding more false positives, at the expense of increasing false negatives.
Therefore, most algorithms apply the cross-species conservation requirement to reduce the number of false positives, despite some risk of increasing false negatives as some miRNAs, such as miR-430 [ 44], lack conserved targets.
Diagnostic methods of TB, nowadays, are prone to delay in diagnosis, increased false negative results and are not sensitive to many forms of paucibacillary disease.
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