Sentence examples for increasing endogenous from inspiring English sources

As mentioned above, FAAH inhibition indirectly activates both CB1 and PPAR-α receptors by increasing endogenous levels of anandamide and OEA/PEA, respectively.

Thirdly, HBK001 can attenuate hyperglycemia and improve insulin resistance via increasing endogenous GLP-1 levels and directly stimulating insulin secretion, all of which cannot be achieved by linagliptin treatment.

These results indicate that rutin attenuates ischemic neural apoptosis by reducing the expression of p53, preventing morphological changes and increasing endogenous antioxidant enzymatic activities.

Roxadustat FG-45922) is an oral hypoxia-inducible factor prolyl-hydroxylase inhibitor that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin.

In the present study, we investigated whether increasing endogenous cannabinoids levels, through the use of FAAH mice as well as the FAAH inhibitor URB597 or the MAGL inhibitor JZL184, would reduce the intensity of withdrawal signs precipitated by the CB(1) receptor antagonist rimonabant in THC-dependent mice.

The role of kaempferol as a precursor that increases Q levels, combined with its ability to upregulate Sirt3, identify kaempferol as a potential candidate in the design of interventions aimed on increasing endogenous Q biosynthesis, particularly in kidney.

Thus, inhibiting DPP4 can slow down GLP-1 degradation and thus increase endogenous bioactive GLP-1 levels12, 12.

Numerous studies seeking new approaches to increase endogenous GLP-1 levels have been reported for potential T2DM treatment.

This suggests that the differentiation of GMPs into Ly6G+ cells is caused by the increased endogenous expression of miR-223 in GMP cells.

To determine the effect of Wnt10b on neovascularization and fibrosis, we generated a mouse line to increase endogenous Wnt10b levels in cardiomyocytes.

We first found that preadministration of the KD for 4 weeks increased endogenous NO generation in the hippocampus.