Sentence examples for increasing efflux from inspiring English sources

Thus, Y667Q was localized within the Golgi at 12, 20 and 30 hours after transfection but demonstrated increasing efflux from the Golgi at 40 hours.

On the other hand, rapid regulation of the gene transcripts MTPc3 and MTPa2 indicates changes associated with divalent cation homeostasis and have the effect of decreasing divalent cation influx into and increasing efflux out of the cytosol.

NSC23925 prevents the increased expression of Pgp and therefore prevents increased efflux and/or decreased influx of drugs during chemotherapy treatment.

These results strongly indicated that the increased expression of Pgp resulted in the decreased intracellular accumulation and increased efflux of Pgp substrates.

Its over-expression results into the increased efflux of therapeutic agents rendering them inefficacious.

Vanishing β2-stimulation following cessation of ritodrine conversely increases efflux of potassium from the cells to increase plasma potassium levels.

The toxicity results from either reduced influx or increased efflux of K+ (Bossemeyer et al. 1989; Jung et al. 2001).

However, such compounds carry higher pharmacokinetic risks, such as low solubility and permeability, and increased efflux and metabolism.

Alternatively, reduced permeability or increased efflux (Black et al., 2014) of the drugs can also occur, thus preventing the drug from gaining access to the target.

In rice line RIL46, Zinc-deficiency tolerance to some extent is due to the increased efflux of MAs (Widodo et al. 2010).

Increased expression of BCRP causes increased efflux and therefore, reduced intracellular accumulation of many unrelated chemotherapeutic agents leading to multidrug resistance (MDR).