Traditionally, according to the "two hit" theory, simple steatosis and NASH have been considered an histological continuum with increasing degrees of severity [ 9].
Hispanic males exhibited high loading factors of both HDL and triglycerides, potentially suggesting that worsening levels of both components are important indicators of increasing degree of MetS severity.
In other words, an increasing degree of observed clinical severity on the ADOS-G was significantly associated with reduced activation on the EFT versus control task.
With regard to the presence of Aβ oligomers in the AD brain, a recent study provided strong support for the progressive accumulation of these toxic forms of Aβ with increasing degree of synaptic loss and severity of cognitive impairment (Pham et al., 2010).
After adjustment for patients' severity, increasing degree of dysnatremia was associated with increasing prognostic impact.
BNP concentrations were found proportional to the severity of embolism, probably due to the increasing degree of right ventricular stress [ 83].
The current study shows a clear association between lower HRV and increasing degrees of DSP severity, which are in agreement with existing literature (18).
In evaluating a cohort of type 1 diabetic subjects representing the spectrum of neuropathy, we found a strong incremental association between lower HRV, as measured by RRvar with deep breathing, and increasing degrees of DSP severity.
The relative improvement increased with the degree of severity of symptoms at baseline, which is consistent with the general expectation.
