The use of multiple detectors, or single multiplexed detectors, can reduce effects of paralysis and increases data acquisition times.
A majority of comparative genomic studies have suggested excess of losses over gains over the last 500 MY (e.g [49], [57], [58], [59], except in Fungi [60]. However, increasing data suggest that intron acquisition is still ongoing (reviewed in [61]).
Before MyType, Tim was a consultant at the Pentagon, where he focused on increasing data transparency within the military acquisition enterprise by introducing custom web services to manage and monitor day-to-day oversight and operations.
Secondly, if only one MDC is used, its total movement path will be longer, increasing the data acquisition delay time, which is inappropriate for certain applications.
However, this approach cannot be used in the top-down HDX MS measurements, which almost always utilize direct infusion of the protein solution to the ESI source to increase the data acquisition window and do not allow the desalting step to be introduced prior to protein ionization.
The increasing number of data acquisition stations and setups in laboratory environments at Wendelstein 7-X does already produce a considerable amount of data by now.
Although community efforts exist for the expert curation of neuroanatomical terms pertaining to brain regions [5] and grass root scholarly collation of neuroscience terminology [6], the continuously increasing pace of data acquisition is paradoxically yielding an ever more fractured lexicon, creating serious impediment to progress.
A variety of factors, in particular the rapidly increasing pace of data acquisition in the life sciences, have led to the proliferation and wide-spread uptake of biocuration as a full-time career.
Recent improved sequencing techniques [ 7– 9] have led to a remarkable increase in data acquisition rates, and have enabled simplified protocols.
