However, subsequent larger studies of IPTc with SP & AQ conducted in Burkina Faso and Mali have shown a substantial reduction in hospital admissions with malaria in children who received IPTc [33] suggesting increased cost effectiveness.
In addition to increased cost effectiveness, simplicity and built-in QA of the PCR-based method, multiplex PCR also has the potential to reveal a different distribution of serotypes circulating in the population compared to culture-positive cases.
There is limited evidence to support cost effectiveness of population screening in rheumatoid arthritis and case finding strategies have been proposed as a means to increase cost effectiveness of diagnostic screening for osteoporosis.
In order to increase cost effectiveness, reduce waiting lists and optimise resources, it is necessary to use tools such as the EPAGE II guidelines, which establish criteria to assess the appropriateness of colonoscopies.
Those innovations, combined with increasing cost-effectiveness in the early 21st century, enabled the routine use of whole genome sequencing in laboratories worldwide, which effectively ushered in a new era of biological discovery.
In a small, saturated franchise, growing pressures for further de-regulation, the inclusion of environmental costs, increasing cost-effectiveness, and intensified competition are among the major forces changing the company's familiar landscape beyond recognition.
