Exact(30)
This novel mechanism for increasing copy number may have more widespread applications than the commonly used pUC high-copy origin of replication mutation.
We first established a standard curve by using increasing copy numbers (5 to 5×108 copies) of the plasmid Oxa-51/pCRII-TOPO in the assay (r = 0.9992, Text S3).
Since CCL3L1 encodes the natural ligand of CCR5 and increasing copy number of CCL3L1 down-regulates the expression of CCR5 on the cell surface [10], the HIV-1 entry-dependent effect of CCL3L1 on CCR5 used to be accepted as the major mechanism that inhibiting HIV-1 infection.
These results indicate a dose-dependent partial rescue with increasing copy numbers of His-GU transgenes.
Tandem duplication is known to be the most frequent mechanism in increasing copy numbers for gene families [ 32].
Clustering decreased with increasing copy number; copy numbers 21 and 22, which included large outbreaks, were the exceptions.
Similar(30)
A positive linear regression coefficient indicates that increasing values of the quantitative outcome are associated with increasing copies of the minor allele in the genotype.
3q22) in the regression on TIBC, indicating that increasing values of TIBC are associated with increasing copies of the minor allele in the rs3811647 genotype.
This explains the increasing copies of kelch motifs ACBPs in B. rapa and B. oleracea (4 copies each).
Increased copy number of a BAC transgene correlates with increased expression of the BAC transgene (Chandler et al. 2007).
None of the newspapers involved did create artificial drama as would have been customary in the 1980s, just to increase copy sales.
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