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In our previous studies [8, 9], we have shown that these large chemical libraries can be efficiently processed in parallel using Apache Spark [10] and scales well with increasing computation power.
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From this rapid growth of data, along with exponentially increased computation power, new visualization technologies, and the realization that the integration of these elements can lead to increased documentation of dynamic and overlaid data, has provided new tools for planning and more efficient engagement with natural, built, and social systems.
Although modern technologies for data generation and computation is neither a necessity for MC estimation (Hammersley and Morton, 1954) nor for multiple testing (Schweder and Spjøtvoll, 1982), it seems clear that their adoption has been driven by increased computer power and data generation technologies such as microarrays.
Power efficiency investigation has been required in each level of a High Performance Computing (HPC) system because of the increasing computation demands of scientific and engineering applications.
The number of SNP does not increase computation time linearly because greater SNP density gives greater power to eliminate surrogates, which can reduce computation time.
The rapid increase in computation power and software complexity have increased the range of applicability of these tools to larger and more complex biological systems, while including important stochastic, geometrical (boundary) and multiscale temporal and spatial effects.
The question has received replies from the continuous developments of theoretical mathematicians and the parallel increase of computer computation power, so that curvilinear models [ 13, 36] are no more a problem also with personal computers [ 3, 17, 40- 42].
Given the increase in computation power using cluster computing during recent years, the ability to split certain calculations over different computers is a valuable aid in analyzing large datasets, such as the one studied in this work.
Recent increases in computation power have prompted enormous growth in the use of simulation models in ecological research.
The current hardware evolution brings increasing parallel computing power that can speed up the computations in FWI.
However, the computation power increases significantly and a compromise between efficiency and quality of results has to be found.
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