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To account for these conflicting observations, we suggest that local environments in some organs select for neoplastic cells bearing mutations increasing cell division rate ("r-selected," as in colon and lung) while conditions elsewhere may select for reduced mortality rate ("K-selected," as in liver and kidney).
Hormones are hypothesized to increase cancer risk by increasing cell division, thereby increasing the risk for genetic errors of various kinds or fixing an initial mutagenic event.
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Humic acids are known to stimulate plant growth through increased cell division, enhancement of uptake of nutrients and water, and enhancement of the soil microbial population (Atiyeh et al. 2002; Chen et al. 2004; Delgado et al. 2002; García-Gil et al. 2004; Xu et al. 2014; Hussain et al. 2017a, b).
The increase in PERKΔC acini size could result from increased cell division, reduced apoptosis or a combination of both.
The presence of mycoplasma-infected MSC led to increased cell division arrest of both CD4+ and CD8+ T cells compared to mycoplasma-free MSC.
From our findings we speculate that AFP may regulate morphogenesis of the liver by inhibiting increased cell division of hepatocytes in embryos.
Considerable evidence support this conclusion: Mutants lacking the β-subunit are hypersensitive to D-glucose and have increased cell division and consequently more LR.
This indicates that increased cell division efficiency, which leads to shorter cells, is always at the cost of aberrant cell division at the poles in strains lacking a functional Min system.
Increased cell division was noted at 4 h.
Driver mutations may increase cell division, reduce cell death, or allow cells to overcome density-limiting effects.
However, cell extrusions and decreasing cell area more than compensate for increased cell division to produce smaller wings.
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