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Adjusting for a fixed-effect of season decreased the variability observed within homes and increases variation between homes.
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Individual, pregnancy, clinical practice and hospital factors not accounted for in the model could contribute to increased variation between-hospital IOL rates.
This intra-cluster correlation leads to increased variation between clusters compared to the variation within clusters.
This would tend to favour increased variation between reviews along the lines we observed.
The order of descriptors was randomised to avoid bias, but this may have increased variation between observers, so the descriptor order will be constant in subsequent validations.
Due to the short case descriptions the physicians had to make their decisions with relatively little information which could have caused increased variation between physicians and some bias in results.
If true, this dynamism would not be seen in technologies such as MethylCap [ 23] that only pull back methylation from CpG dinucleotides, and could potentially contribute to the increased variation between ESC replicates.
For the scenario (4) we varied two parameters: (4a) introduction of rain cycles with increasing period length PL, i.e. longer phases of favorable and unfavorable rain conditions and, (4b) increase in intra-cycle variation ICV, i.e. increasing variation between alternating favorable and unfavorable periods within one rain cycle.
Reliability increases as variation between GPs increases and with the number of patients per GP [ 7].
It is also likely that there would be increased variation in measurement between participants.
This suggests that the increased variation observed between different full-term placentas is not necessarily a by-product of increasing methylation across gestation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com