Sentence examples for increases to the mutation from inspiring English sources

Increases to the mutation rate beyond the optimal value at mutation selection balance may therefore prove generally undesirable.

However, under conditions of environmental stress, a more convenient evolutionary strategy for these organisms would be to increase the mutation rate to get rapid adaptation [14] [16].

For each course of evolution under a fixed mutation rate, the proportionality between Vg and Vip is derived, since the genetic variance increases roughly proportionally to the mutation rate[18].

To increase the mutation efficiency, we designed gRNA vectors containing one to three gRNAs directed against different regions of the same gene.

Consequently, even if selection is acting to increase the mutation rate of sexually selected genes, it seems unlikely to impact on minisatellite mutation rates; molecularly, the two process have too little in common.

For each population, we propose an adaptive mutation rate tuning method to increase the mutation rate based on fitness values and remaining generations.

Can therapy be designed to increase the mutation rate in tumors beyond the optimum derived in this paper, resulting in lethal mutagenesis?

These gene losses are expected to increase the mutation accumulation rate.

Late-replication timing is known to increase the mutation rate (Liu et al., 2013).

The vaccine strain candidate was further attenuated by UV irradiation to increase the mutation rate of the viral genome (4, 37).

In addition, sites for the attenuation of the mtDNA transcription mechanism [ 43] (i.e. located in the vicinity of nad3 and cob) may also be important to increase the mutation load for neighbour genes.