In practical terms, using low amounts of siRNA reduces the costs and increases the specificity of the experiment by avoiding non-specific knockdown of unrelated proteins and preventing the cell from undergoing a viral response.
Our overall plan also greatly increases the specificity of mechanisms to support implementation, educational outreach programs, and quantitative metrics that clearly measure success.
Immobilized substrate increases the specificity and sensitivity of LF-catalyzed substrate hydrolysis compared with the solution phase assay.
Since the FokI nuclease functions as a dimer, pairs of zinc-finger domains are designed to bind upstream and downstream of the cut site which increases the specificity of the complete ZFN to 24 36 nucleotides.
Model order progression (MOP), the predicted optimal variant, gradually increases the specificity of the relations between variables, whereas model elaboration progression (MEP) gradually expands the number of variables in the task.
Conclusions: Sialometry and biopsy tests presented different performances in primary Sjögren's Syndrome and secondary Sjögren's Syndrome; the positivity of the association of both tests increases the specificity for Sjögren's Syndrome (95%).
Combining an abdominal circumference (AC) or femur length (FL) z-score less than -2 with the total EFW improved the specificity and PPV but decreased the sensitivity.A combination of a small AC or FL along with EFW increases the specificity and PPV, but decreases the sensitivity of predicting SGA.Journal of Perinatology advance online publication, 26 January 2017; doi 10.1038/jp.2016.275.
Lesion characterisation on the CT portion of the PET/CT study is therefore of utmost importance as it increases the specificity of PET/CT reporting [10].
However, it was reported that the introducing of a "spacer group" between the drug molecule and the carrier protein usually increases the specificity of the produced antibody [34].
Although the introducing of a "spacer group" between the hapten molecule and the carrier protein usually increases the specificity of the antibody aimed to be produced [13], however the reactive COOH group of ROS is adequately spaced (6 carbon atoms) from its aromatic strong epitopic moieties [14] that is characteristic for the ROS molecule.
The addition of routine laboratory test results such as a complete blood count or chest radiographs expectedly increases the specificity and positive predictive value of these ILI definitions.
