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However, whether OSA itself initiates or increases the progression of these abnormalities is entirely unknown.
This change induces systemic inflammation and potentially increases the progression of chronic arthritis.
After breast-conserving surgery, adjuvant radiotherapy to the involved breast significantly increases the progression free survival and reduces the breast cancer death rate by about a sixth [ 1].
These observations suggest that early exposure to an LP diet accelerates the development and increases the progression of atherosclerotic lesions in young adult offspring.
For instance, oral exposure to arsenic in mice not only increases the incidence but also greatly increases the progression of skin cancers associated with ultraviolet irradiation (Rossman et al. 2004).
It has been demonstrated that cyclin D1 overexpression increases the progression of PCa [ 55] and cyclin D1 knockdown reduce cell proliferation and increases sensitivity to radiotherapy and chemotherapy [ 56].
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Based on these findings, we conjecture that the absence of cystatin C also may increase the progression and growth of other types of tumors.
Oestrogen and prolactin are thought to increase the progression of murine SLE.
Likewise, mothers in Malawi [ 19] felt that exclusive breastfeeding would increase the progression of HIV.
These LMW isoforms are nuclear and functionally active because they increase the progression from G1 to S phase [ 11].
HIV coinfection has been shown to increase the progression of liver fibrosis [ 37, 38] and is likely to eventually increase the incidence of the tumor [ 33].
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