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Heterogeneity, particularly intratumoral heterogeneity, increases the challenges of cancer subtype classification.
The implementation of multiple-use MPAs increases the challenges of communicating awareness of MPA boundaries and permitted activities.
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"This is good news on the conservation front but bigger populations in bigger areas increases the challenge of managing land, human and animal conflict," he told AFP. "There (also) has to be some other place far away from Gir (for lions) so that in a time of catastrophe, we don't lose the population".
This increases the challenge of balancing intermittent generation with demand fluctuation.
Differently, the high surface area of porous structure increases the challenge of controlling the rapid corrosion of magnesium scaffolds (Aghion and Perez 2014; Cheng et al. 2016).
The low number of constructs shared among studies, combined with the few studies published in this field, increases the challenge of recognizing overall trends within and among constructs.
The RTG demand behaviour is mainly non-smooth, volatile and without obvious patterns or seasonality in the demand time series which increases the challenge of forecast the crane load.
Since each individual gene may have an independent but small effect on the susceptibility and clinical manifestations of VKH disease, this increases the challenge of finding the genetic culprit in pathogenesis of VKH disease.
The lack of an experimental tradition in glacial geomorphology leaves many research avenues open for exploration but also increases the challenge of demonstrating the relevance of experimental results to theoretical and field-based studies.
This increases the challenge of quantifying drinking in all new patients.
However, this only increases the challenge of ensuring those centers are staffed.
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