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More interestingly Hh signalling is also active in human breast cancer stem cells and studies on in vitro culture systems showed that an activation of this pathway with Hh ligands promotes the self-renewal of mammary stem cells, and also increases proliferation of mammary progenitor cells as reflected by increased numbers of mammosphere-initiating cells and increased mammosphere size [ 43].
We show that conditioned medium from cAMP-treated hMSCs increases proliferation of various cell types and also induces osteogenic differentiation, whereas it has differential effects on migration.
In conclusion, our results suggest that retinoic acid increases proliferation of human osteoclast progenitors and that it inhibits RANK-stimulated osteoclast differentiation by suppressing RANK.
Kimura et al. have demonstrated that AIF-1 is expressed in synovial and mononuclear cells in RA synovial tissue and increases proliferation of cultured synoviocytes and IL-6 production by these synoviocytes and PBMCs [41].
ATF4 subsequently increases proliferation of osteoblasts and/or preosteoblasts via modulation of cyclin D1 protein, and attenuates apoptotic death in osteoblasts and osteocytes, resulting in a significant increase in the numbers of osteoblasts and/or osteocytes.
MiR-133 increases proliferation of C2C12 myoblasts, whereas miR-206 and miR-1 promote differentiation [ 16].
Similar(32)
The increasing proliferation of smartphones is what encouraged executives at People.com to amend their approach to celebrity news.
One is the increasing proliferation of casinos, not only in states that permit gambling but also in states that previously did not allow casinos.
"Satellite TV Creates Sports Bar in the Sky" (March 28) presents the increasing proliferation of television sets in public spaces as if it were a good thing.
Russo told an audience at the Wizard World New Orleans convention that film-makers planned to deal with an increasing proliferation of costumed heroes in Marvel's "cinematic universe" by removing some of its key players.
Also, the increasing proliferation of smartphones today gives us email wherever we go.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com