Your English writing platform
Discover LudwigSuggestions(5)
Exact(3)
For antagonistic pleiotropy (for which there is the most empirical support, e.g., [30]), this implies that positive selection on alleles associated with increases of survival or fertility at young ages must be large enough to compensate for non-negligible negative selection on survival at old ages, highlighting the role of trade-offs in the evolution of senescence.
Moreover, median age at diagnosis decreased, further contributing to increases of survival and prevalence of prostate cancer survivors.
In this scenario, BRCA1 appears an excellent candidate gene for testing the impact of metformin on the theory of evolutionary theory of antagonist pleiotropy [ 80], for which the positive selection on alleles associated with increases of survival or fertility at young ages must be large enough to compensate for non-negligible negative selection on survival at old ages.
Similar(57)
The combination of the two drugs produced a dramatic increase of survival lasting several months.
A randomised control trial of heart rate (HR) control in septic shock showed an increase of survival for the patients receiving esmolol1.
In addition, in in vivo LPS-induced mouse endotoxemia model, thio-Cl-IB-MECA exerted the increase of survival rate compared to vehicle-treated mouse.
However, the similar increase of survival rate was not obvious for 143B cells.
We observed an increase of survival without moderate or severe disability.
No trial was big enough to detect the likely increase of survival, which is 5%.
This could explain the increase of survival in cancer patients enrolled in screening campaigns, without a corresponding reduction of mortality.
A CD8+ T cell response, specific cytotoxicity and an antibody response were activated leading to a significant increase of survival.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com