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As expected ectopic expression of SF2/ASF increases inclusion of the alternative exon, relative to the cells depleted for SF2/ASF (Fig. 4B).
UPS impairment has also been observed in cell culture and animal models overexpressing mutant huntingtin protein [16] [19],, and consistent with data proposing a protective effect of aggregation due to sequestration of toxic species, treatment with a compound that increases inclusion formation prevents huntingtin-mediated proteasome inhibition [19].
Although we demonstrate that Pol II slows down at exons, presumably to facilitate splicing, we could not determine whether a slowly transcribing Pol II increases inclusion of exons.
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Crude protein intake increased with increased inclusion level of Sesbania in the diet.
It is important that we all take collective responsibility for increasing inclusion across books.
For some couples, it is another welcome sign of their increasing inclusion in the American mainstream.
He had been working part-time with the campus's chancellor, R Bowen Loftin, on a plan to increase inclusion and diversity at the school.
Politics tells a story of increasing inclusion; economics tells a story of a widening and permanent class divide.
The conference in July will hear more proposals about increasing inclusion – encouraging schools to retain and educate the most disadvantaged pupils – and how to broaden accountability measures while reducing reliance on narrow indicators such as the EBacc subjects.
Increasing inclusion level of algae biomass caused an increase in whole body lipid.
The potential ruminal degradation of the diets was markedly and linearly increased with the increasing inclusion of the by-product.
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