Sentence examples for increases in specificity from inspiring English sources

Use of future additional filters and/or genus-adapted PWMs may lead to incremental increases in specificity, perhaps with minimal loss of sensitivity.

Indeed, this method of recognition has been proposed to be highly appropriate for biological interactions that require lower affinities, uncoupling increases in specificity from increases in affinity.

We did not observe such increases in specificity for typhoid, based on the proportion of patients with various Widal titers who had dengue antibodies.

Serum lactate dehydrogenase (LDH) levels have been integrated into current staging regimens (Balch et al., 2009) and elevation of LDH levels increases in specificity as disease progresses (stages II (83%), III (87%), and IV (92%)).

The large increases in specificity (up to 10-fold) are mostly a result of an increase in the apparent cooperativity, which results in a much larger denominator when calculating the specificity constant (kcat/ K1/2 nH ).

Increases in specificity and decreases in sensitivity with increasing threshold (and the converse for decreasing threshold) were significant for performance home measurements but not significant for the clinic measurements.

With enhanced CRISPR targeting through judicious site selection, improved Cas9 variants, optimized gRNA architecture or additional cofactors, an increase in specificity throughout the targeting sequence will likely result, placing greater importance on the identity of the 5′ nucleotide.

Similarly, any increase in specificity achieved by a shift to the right will be more than offset by a decrease in sensitivity.

The major driver for this improvement in impact on patient management has been the increase in specificity, a traditional weak-point of conventional bone scintigraphy (Dobrindt et al. 2015).

The trend of increasing specificity with quantitative analysis is consistent with a study comparing initial DaT scan imaging diagnoses with 6-month clinical follow-up (Jennings et al., 2004), which reported an increase in specificity from 80%to100%0% when utilizing a cutoff of 30% decrease in age-corrected putamen uptake from normal controls to define abnormal DaT scans.

While an interesting conclusion for practitioners, future research should look at more precise deliniation of such a theme to see if an increase in specificity would lead to more conclusive outcomes in terms of the internal benefits to organizations looking to implement sustainable innovations.