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Studies with breast cell lines, showing that 5α-pregnanes stimulate proliferation and decrease attachment of cells [ 1, 2] prompted us to suggest that neoplasia in human breast may be promoted by increases in ratio of 5α-pregnanes:4-pregnenes.
As shown in Figure 4a, PKC α expression was increased 4.2-fold in PKC α-expressing vector-treated RD cells, associated with significant increases in ratio of phosphorylated (P -ERK to ERK (2.4-fold), P -ERKorylatod p-38 (P-p38MAPK) to p38MAPK (1.8-fold), and P-JNK to JNK(2.4-fold) comparERKwith the ratio of P-MAPK to MAPK in controls.
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When non-dimensional ratios were used, arranging the ratios such that their changes resulted in corresponding changes in the output (e.g. increases in ratios to cause increases in output values) improved network performance.
The levels of HDL-C did not significantly decrease at 24 h after doses 6 and 7, which led to marginal increases in ratios of ApoA1/ApoB (Fig. 6).
It may be also noted that the rate of increase in frequencies increase with an increase in hub radius ratio and the increase in ratio of τ b /τ h.
However, under increasing drought conditions, increase in ratio of intercellular CO2 to ambient CO2 concentrations along with reduced WUE showed the role of non-stomatal limitation of photosynthesis.
An increase in ratio of Cr2O3 to Al in the pack composition tends to form a chromide coating, which is very poor in high temperature oxidation resistance.
The degree of facilitation was determined as the increase in ratio of the initial slope of the second response over first response in each pair.
Our results demonstrated an increase in ratio of MHY7 MYH6 in offspring of obese dams from weaning.
This increase in ratio has been noted in the past [ 27].
In both cases the enrichment led to significant increase in ratio of spectra assigned to oxidised Met peptides to all assigned spectra (Table 1).
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