Although it also was hypothesized that increases in AM could be correlated with insecticide resistance (Hiroyoshi 1980; Franco et al. 1982; Kence and Kence 1992), this does not appear to be the case for reasons discussed above.
Interestingly, when examining the effect of PGF2α and hypoxic treatment of primary endometrial explants, increases in AM expression were only observed in explants taken during the secretory phase of the cycle.
Comparing the pre-study year to the first and second study year, respectively, the only consistent changes over both years were increases in AM medication use and psychotherapy.
A role for scavenger-type receptors (SR) in AM uptake of components of ROFA and CAP was identified by marked inhibition of RAS increases in AM pretreated with the specific SR inhibitor polyinosinic acid.
The possible involvements of phosphate, which generally increases in AM plants, and of variations in sugar transport and in hormone homeostasis, signalling and interactions are also discussed.
As expected, we have found that the AECII conditioned medium indeed showed greater increases in AM migration and superoxide production compared to the AM-conditioned medium, particularly at earlier times (6 h, Figure S1C).
