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Taken together, our results demonstrate that chronic cobalt exposure increases acute nociception (TF, HP and first phase of the orofacial formalin pain) but has an antinociceptive effect on the inflammatory pain induced by orofacial formalin injection.
Since sepsis likely increases acute mortality compared with other conditions, studies to address this question would have to separate acute from post-acute mortality, adjust for confounding variables, and identify appropriate control populations.
While the mechanisms by which PM increases acute cardiovascular events are not fully understood, we and others have suggested that the consequences of PM-induced lung inflammation on hemostasis play an important role in this response [1], [3], [9], [11], [14], [15], [37], [38].
As the use of these agents increases, acute and chronic exposure has become more common.
The toxicities reported from the randomized trials suggest that hyperfractionation with dose escalation increases acute mucosal toxicity, but does not seem to induce significantly more severe late effects compared with conventional fractionation.
Elevated TLR4 expression on mast cells and macrophages in the spleen and heart of CVB3 infected males not only increases acute myocarditis but induces expression of the profibrotic cytokine IL-1β resulting in cardiac dilatation and heart failure later [ 13- 15, 36].
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Treating to a lower blood pressure (BP) may increase acute kidney injury (AKI) events.
Intra-myocardial injection of CDCs encapsulated in these hydrogels greatly increased acute myocardial retention (p = 0.001).
The last year of life is characterized by increased acute care utilization and hospital deaths.
New emerging strains of noroviruses (NoVs) often increase acute gastroenteritis (AGE) outbreaks worldwide.
Both surgical groups had an increased acute care incidence of pneumonia and DVT and PE.
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