Sentence examples for increased transformation of from inspiring English sources
For example, MK and MX both induce P450-dependent oxygenases (Lehman-McKeeman et al. 1995; Mersch-Sundermann et al. 1996, 2001; Suter-Eichenberger et al. 1999) and therefore could cause increased transformation of other environmental chemicals that are mutagenic in their transformed form such as benzo(a pyrene, 2-aminoanthracene, and aflatoxin B1 (Mersch-Sundermann et al. 1996, 2001).
Progression to CKD results from an inadequate resolution of the acute insult following AKI, with persistent inflammation, increased transformation of pericytes into myofibroblasts in response to tubular injury, and consequent build-up of extracellular matrix and vascular rarefaction, leading to permanent scarring in renal structure and changes in renal function [102].
We thus show that MET signalling can lead to increased transformation of colon epithelial cells independent of Wnt signalling and in this way could play an essential role in the onset and progression of colorectal cancer.
The increased transformation of activated macrophages into foam cells in the lining and sublining layers of hyperlipemic animals with AIA occurs as a result of the enhanced uptake by their scavenger receptors of oxidized low density lipoproteins (oxLDL).
Positive correlation between the degree of AhR overexpression and states of increasing transformation of mammary epithelial cells appears to occur in the absence of any exogenous AhR ligands.
Hanley [ 12] points out that single test ROC analysis is robust to the violation of the normality assumption if there exists a monotonely increasing transformation of the test scores that yields a normally distributed result.
Furthermore, correlation is not invariant under non-linear strictly increasing transformations of random variables.
Inhibition of the DDR kinases ATM and Chk2 markedly increased transformation efficiency of primary B cells.
Here, we show that overexpression of wild-type or a constitutively activated form of MET in colon epithelial cells leads to increased transformation irrespective of Wnt signalling.
However, when their contents increased, transformation temperatures of Ar1 and Ar3 is decrease during RCR + ACC process.
These stem cells in the hilum may have increased transformation potential after inactivation of Trp 53 and Rb 1 and be the origin of high grade serous carcinoma.
