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Increased amounts of metabolites involved in tyrosine metabolism coincides with earlier reports of increased transcripts of genes involved in tyrosine metabolism in peripheral blood mononuclear cells from CD patients [21].
Moreover, the increased transcripts of MIA genes also resulted in higher accumulation of specific alkaloids in transformed leaf samples.
Under water stress, the transgenic plants had increased transcripts of NCED mRNA, elevated leaf ABA concentrations, increased concentrations of proline, and a significant increase in drought resistance.
To identify biomarkers for ovarian cancer, Abbott et al.[ 68] first studied the expression of glycosyltransferases in endometrioid ovarian tumor tissues using quantitative real-time PCR and identified increased transcripts of enzymes responsible for core fucosylation (FUT 8) and bisecting glycans (GnT-III).
Different types of secretion may be increased as indicated by increased transcripts of a type I system (DVU1013) and increased protein levels of an annotated type III protein secretion system (DVUA0115).
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Macrophages isolated from spleen of LD-infected Balb/c mice showed increased IRE IRP interaction (Fig. 5A) and resultant increased transcript of TfR1 (Fig. 5B).
Therefore, B-deficiency might down-regulate the accumulation of LCR mRNA in C. sinensis roots due to increased transcript of miR394 (Additional file 3), thus improving the tolerance of plants to B-deficiency.
We have reported that metastatic prostate cancer from androgen deprived individuals contains supraphysiologic levels of tissue testosterone in the presence of increased transcripts encoding enzymes of steroidogenesis [ 18].
Further work is required to determine the exact mechanism of increased transcript abundance of GRE3 in the presence of the APJ1 CBS1502 allele.
Down-regulation of AtMYB32 increased transcript levels of COMT gene involved in lignin biosynthesis and reduced the levels of DFR and ANS genes associated with proanthocyanidin biosynthesis [ 69].
Increased transcript levels of genes involved in metabolism of nitrate at the onset of germination implies its use as a source of nitrogen.
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