Sentence examples for increased substrate specificity from inspiring English sources

To circumvent this challenge, the intracellular β-glucosidase would need to have an increased substrate specificity for GX and lower activity for cellobiose.

The MMP family is divided in subfamilies and MMP1, together with MMP8 and MMP13, forms the collagenase family, because they display increased substrate specificity for collagen.

In the case of Spn43Ac, both the full length protein and the cleaved core serpin are active proteinase inhibitors in vitro, but the core serpin shows increased substrate specificity for porcine pancreatic elastase (PPE) [ 49].

Ndfip1 (Nedd4 family-interacting protein 1) is an adaptor and activator for Nedd4-family ubiquitin ligases for increasing substrate specificity.

In some instances, the ATP concentration was lowered to 10 μM to increase substrate specificity.

At this stage, β-MPP has acquired a dual function, as observed in Neurospora, while in plants, cp2 was likely replaced with the α-MPP to increase substrate specificity of the membrane-associated complex.

In contrast to single recognition, difunctional ones increased the substrate specificity remarkably.

In vitro, the fusion protein was capable of selectively binding PP-1C and increasing the substrate specificity of the phosphatase towards myosin 13.2 +/- 3.5-fold (S.E. of the mean, n = 3).

Conversion of proline to alanine was also found in Pokkali and Nona Bokra alleles of the HKT1 5 gene which is supposed to increase the substrate specificity (Cotsaftis et al. 2012; Negrão et al. 2013).

Both the blocker and the biosensor have been shown to increase the substrate specificity of the ribozyme's cleavage by several orders of magnitude compared with the wildtype HDV ribozyme [29].

Emerging technologies are enabling ultra-high-throughput screening of combinatorial enzyme libraries to identify variants with improved properties such as increased activity, altered substrate specificity, and increased stability.