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Thyroid follicular cell tumors arise in rodents from mutations, perturbations of thyroid and pituitary hormone status with increased stimulation of thyroid cell growth by thyroid-stimulating hormone (TSH), or a combination of the two.
Deleting intervening DNA to produce 0.23-kb spacing increased stimulation to >500-fold.
If that's not green enough, go minimal with the Callisto Clear Glass Dildo: fracture-resistant, it retains heat and cold for increased stimulation, and you can even recycle it.
Constructing a promoter with two 4xH4REs 0.25 kb apart by duplicating the 4xH4RE fragment increased stimulation to >1000-fold >1000-fold
These openers can produce excessive soil throw which creates problems such as increasing the depth of soil cover on adjacent furrows, herbicide contamination above seed in adjacent furrows, increased stimulation of weed seed germination and furrow moisture loss.
While the addition of lipofectin to DNA increased stimulation by all DNA, it did not change the relative potency of the DNA tested.
Thus, the disrupted function of interneurons due to loss of inhibitory control and increased stimulation could contribute to the cascade of events that lead to persistent chronic pain.
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In light of these studies, there appears to be no clear relationship between age-related changes in adrenergic nerve density, increases in circulating plasma NA levels reported by others and increased stimulation-evoked NA release in our earlier studies.
In our studies in adrenergic nerve endings in tail arteries, the SERCA blocker, thapsigargin, increased stimulation-evoked NA release in young arteries with no change in arteries from old animals (Tsai et al., 1998).
Similarly, in adrenergic nerve endings in tail arteries, dinitrophenol increased stimulation-evoked NA release in arteries from old animals with no significant effect in young arteries (Tsai et al., 1995).
As TTX prevents electrically evoked noradrenaline release from SCG neurons (Boehm, 1999), tritium overflow was stimulated by exposing the cultures to 25 mM KCl for 2 min. Under these conditions, ADP also increased stimulation-evoked tritium overflow and left the spontaneous outflow unaltered.
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