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Load increased stance time.
Moreover, additional load increased stance time.
The results similarly showed that additional load significantly increased stance time of FL and HL, which indicates concurrent walking velocity decreased.
Diabetic patients with peripheral neuropathy have lower gait velocity, decreased cadence, shorter stride length, increased stance time and higher step to step variability compared with healthy controls [ 3].
The authors suggested as a possible mechanism for the increased stance time in this spontaneous OA model that the knockout mice adapted with an altered locomotion pattern (increased percentage stance time) to potentially reduce peak joint forces and thus protect the hindlimbs during walking.
Depletion severity was found to correlate with compensatory changes such as increased stance time of the other three paws and diagonal weight shift to the ipsilesional hind paw.
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Induction of OA in transforming growth factor β1 injected mice by treadmill running also led to increased stance times and decreased swing time (15).
Analysis of type IX collagen deficient mice, which develop OA spontaneously, revealed reduced stride length and increased stance times compared to wild-type mice (27).
Notably, an association of OA joint damage and increased percentage stance time (at a standard velocity) was also recently reported in a study using 9-month-old type IX collagen-deficient (Col9-/) mice [ 34].
Increase in stance time on paretic side was noticeable (without vibration versus StMCV mode p = 0.1014 and versus SpCV mode p = 0.2106) but not significant enough to have p-value <0.05.
In either case, it is clear that OA patients adapt to achieve walking conditions which increase percentage stance time and thereby stabilize the affected limb; however, in patients with symptomatic OA, this strategy is accompanied by higher than normal peak loading and higher than normal loading throughout stance time [ 45].
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