Sentence examples for increased sensitivity to neutralization from inspiring English sources
Four of the five patients' viruses evolved increased sensitivity to neutralization by anti-V3 mAbs.
Of the four patients (ITM60, NYU104, 3506 and ITM27) whose sequential viruses exhibited increased sensitivity to neutralization by anti-V3 mAbs, those from patient ITM27 exhibited the weakest increase in neutralization sensitivity (Figure 2h).
HCVpp-H77 released from IFNα-treated cells showed an increased sensitivity to neutralization by anti-SR-BI, showing an median inhibitory concentration (IC50) of 0.06 μg/mL compared to 0.9 μg/mL for untreated virus, but no change to anti-CD81 (Fig. 4D,E), suggesting that virus released from IFN-treated cells had a reduced dependency on SR-BI for entry.
(f) Increased sensitivity to light and sound?
Increased sensitivity to light and sound II.
Increased sensitivity to pain [6].
Increased sensitivity to cold.
Specific glycans are known to mask the CD81 binding site and mutation of these sites leads to increased CD81 binding and sensitivity to neutralization by patient sera and mAb (Falkowska et al., 2007; Helle et al., 2007, 2010; Pantua et al., 2013).
However, virus sensitivity to neutralization by different V3 mAbs often varies, indicating that access to V3 is not restricted equally for all antibodies.
These differences likely contribute to the difference in sensitivity to neutralization.
