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Rigid bridges such as those provided by bispidine are discussed in terms of increased log K1 values, and sharply increased selectivity for smaller metal ions.
Minor groove binding ligands with increased selectivity should produce a greater pharmacological response for a given dose than non-selective binders.
The Critical Need for Increased Selectivity, Not Increased Water Permeability, for Desalination Membranes.
We have shown that the Al@Cu2O antenna-reactor complexes also yield increased selectivity over traditional thermal-driven reactions.
They target increased selectivity and specificity associated with drug action.
This often leads to increased selectivity towards large cations.
Alternatively, non-linear interactions between specific glomeruli could confer increased selectivity or sensitivity for ethologically important odors.
Specific thiazolobenzoxepin 8-substitution was identified that increased selectivity over PI3Kβ.
Modification of the P1 moiety leads to an increased selectivity versus trypsin.
A procedure for obtaining increased selectivity in a diastereoselective double ring-closing metathesis reaction is presented.
It leads to highly active catalysts, which displayed increased selectivity to acrylonitrile.
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