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However, ECT of tumors statistically significantly increased radiation response of the tumors (Table 2, Figure 3).
Exposure of cells either to BLM, electroporation or ECT statistically significantly increased radiation response of LPB cells.
In conclusion, results of our study show that ECT with BLM greatly increased radiation response of LPB tumors.
The results demonstrated that ECT increased radiation response of cells and tumors, and that the predominant underlying mechanism was increased cisplatin accumulation in the cells of tumors [ 20- 22].
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It is conceivable that the scheduling of weekly cetuximab on this trial produced sufficient vascular normalization to improve oxygenation and increase radiation response.
Likewise, YB-1 siRNA increased radiation sensitivity.
An increased tumour radiation response has been observed with A4.6.1 (Lee et al, 2000), but there are no data available regarding the effect of the antibody on the tumour availability of anticancer drugs.
Increase in radiation response was the lowest when the cells were exposed to BLM (EF = 1.19), probably due to low BLM concentration and a very short exposure time.
It also increases radiation exposure.
Gamma radiation decreased pesticide levels proportionately with increasing radiation doses.
Antiangiogenic therapy increases tumour radiation response, further supporting the new concept of 'normalising tumour vasculature' (Gorski et al, 1999; Lee et al, 2000; Kozin et al, 2001).
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