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As before, increased presentation to type B T cells was observed in the presence of all three stimuli (Fig. 2A), while presentation of peptide to the type A T cells (3A9) showed some reduction at higher peptide concentrations but was not grossly affected (Fig. 2B).
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However, amplifying the level of viral antigens to increase presentation to adaptive immune cells could counterbalance this potential danger.
Increasing presentations to emergency departments have led to overcrowding, long waiting times and suboptimal health system performance.
This approach was recently used to increase presentations to GPs and referrals for chest X-rays, and led to a 27% increase in lung cancer diagnoses in intervention areas compared with controls, although this difference was not statistically significant.
Therefore, the increased presentation of peptide to type B T cells cannot simply be explained by upregulation of costimulatory molecules.
However, in cancer cells, overexpression of cyclin B1 leads to increased presentation of the peptide on the cell surface and thus T-cell recognition.
This causes increased degradation by the ubiquitin pathway, which leads to increased presentation of cyclin B1-derived peptides on the surface of cancer cells compared with normal cells [ 8], which in turn may lead to more efficient T-cell recognition.
We first determined if the increased presentation of peptide was specific to type B T cells.
The reason for increased presentation of STMΔhfq vaccine strain could be due to lack of functional SPI-2 [28], [42], [42] or decreased production of nitric oxide (NO).
The present study demonstrated the relationship between low birth weight and increased presentation of MetS components in Chinese adults.
If you think about the British psyche right now, I saw doctors' reports of increased presentation of people concerned about their mental health, for instance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com