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ChIPs performed on primary APL cells showed an increased occupation of H3K27me3 at the TSS of PRDX4 (Figure 3A), which was not observed in AML samples expressing PRDX4.
Conserved transcription factor binding sites were identified in identically clustered genes within a common GO term and SREBP-1 and FOXJ2 depicted increased occupation of their respective binding elements in the presence of TNFα.
Hence, it is likely that the P6' Leu residue in the helical PLMs not only stabilizes their helical conformations, but also increases inhibitory potency via increased occupation of the enzyme's substrate binding cleft.
As compared to wild-type animals, outside of lethargus unc-31 mutants exhibited increased occupation of the quiet wakefulness state, a fragmented active wakefulness state, and overall lower velocities.
Most bands were applied decades before tracking devices (1960s 1990s versus 2004 2010), so increased occupation of the Gulf of Mexico could reflect a southerly shift of gannets during winter.
We also showed that 5-dAzaC induced demethylation of the 5' flanking region of HSD17B1, leading to increased occupation of the promoter by Polymerase II, and increased transcript and protein levels in HT29 and SW707 CRC cells, which contributed to the increase in E2 formation.
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Moreover, as a direct consequence to the increasing occupation of coastal areas, the cost related to natural hazard has been dramatically increased (Adger et al. 2005).
There is a high prevalence of M ozzardi in some riverside communities in the Amazon with the increasing occupation of the rainforest. 2 16 Previous studies in Coari city showed average infection rates of between 13.3% and 18.9%, with a higher prevalence in rural areas and older patients.
"Senator Fischer has a history of getting broad support for her bills," Mr. Trost wrote in an e-mail, citing as evidence a measure she pushed through this year to control the ability of cities to increase occupation taxes.
The breadth of adaptive radiation attainable by an invading lineage decreased with increasing niche occupation of the resident community.
Using reads with errors or contamination can result in false positive assemblies, which will artificially increase the occupation of bins and thereby complicate the modeling.
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