Sentence examples for increased numbers of cell from inspiring English sources

This genetic variability can be attributed to the often higher mutation rates, multiple selective hurdles, variable micro-environments, and increased numbers of cell generations that characterize cancers.

In such experiments, a decreased collagen fibre organization and increased numbers of cell nuclei were observed [ 36, 37].

Cancer increases with age, as there are increased numbers of cell divisions, more accumulation of somatic mutations, and declining abilities to suppress cancer (Cancer Research UK 2012; American Cancer Society 2012).

Instead, we observed increased numbers of cell protrusions in cells microinjected with p110αE545K/p85α and a higher affinity binding of p110αE545K/p85α to activated Cdc42, providing some preliminary evidence that point mutations in PIK3CA may affect protein protein interactions in addition to its enzymatic activity.

During microinjection experiments to assess PM recruitment of wild-type and mutant PI3Kα, it was observed that cells microinjected with p110αEEE545K/p85α exhibited increased numbers of cell protrusions compared with cells injected with either the control Cy3-ovalbumin, p110αEEWT/p85α or p110αEEH1047R/p85α.

In all PV samples analyzed, there were increased numbers of cells with a HSC phenotype (CD34+CD38-CD90+Lin) compared with normal samples.

We next asked if gain in PDGFRα expression in absence of SCL reflected increased numbers of cells adopting non-blood cell fates.

We observed higher contents of fibrosis in the border zone as well as increased numbers of cells positive for TCF21, which is also expressed in epicardial cells.

For example, since the initial steps of biofilm adherence are lysis dependent (Fig. 1), increased numbers of cells used to initiate biofilm formation may lead to a proportionally increased number of cells undergoing cell lysis and, consequently, an enhanced dependence of biofilm adherence on eDNA and increased sensitivity to DNase I treatment.

In LβT2mPttg cells and in αT3 cells, clusterin suppression led to increased numbers of cells incorporating BrdU respectively (p<0.05) (Figure 8C).

When we treated wild-type mouse epidermis with TSA, increased numbers of cells with H4monoK20 were found in the IFE, hair follicles and sebaceous glands (Fig. 4A,B).