Sentence examples for increased mutations from inspiring English sources

A nuclear gene was analyzed to determine whether it, too, had increased mutations in RA, and thus reveal whether the changes in mutational frequency were specific to mitochondria.

There was convincing evidence, the study concluded, that — in a fraction of cases — increased mutations found in the sperm of older men meant that they were more likely than their younger counterparts to father children with autism or schizophrenia.

The most striking thing to me about the online reaction to the recent study concluding that, in a fraction of cases, increased mutations found in the sperm of older men meant they were more likely than their younger counterparts to father children with autism or schizophrenia was the reaction that wasn't.

Importantly, increased mutations of PIK3CA have also been described in HPV-driven HNC suggesting a potential role for the PI3k/Akt pathway in HNC [86].

In yeast cells, cadmium increased mutations as much as 2000-fold, and up to 50% of spontaneous mismatches were left unrepaired.

Right-sided primary site in microsatellite stable mCRC was associated with shorter survival, older age at diagnosis, increased mutations, and enrichment of oncogenic alterations in KRAS, BRAF, PIK3CA, AKT1, RNF43, and SMAD4 compared with left-sided primaries.

This is a recurrent-genetic mutational model, since it invokes increased mutation due to peculiarities of species' genomes (retroelement invasion).

The increase of mutational frequency was confirmed: again, the newly recirculating B cells showed increased mutation rates.

Research shows that genome-wide hypomethylation leads to increased mutation rates and instability of chromosomes.

Increased mutation burden and defective DNA repair are associated with response to immune checkpoint inhibitors in several other cancer types.

Higher levels of DNA damage not only cause increased mutation, but also cause increased epimutation.