Sentence examples for increased mutation rate from inspiring English sources

In this case, the newly arisen genetic variation would be due to increased mutation rate, rather than due to release of the already present but hidden genetic variation in the phenotype.

Lawrence Loeb, a pathologist at the University of Washington, Seattle, says that if the researchers can discover the mechanism of the increased mutation rate, it could provide a new avenue of treatment for any cancer cell that uses it.

Genetic changes in bacterial genomes come from either random mutation during replication or "stress-directed mutation", where genes involved in a particular growth-limiting process have an increased mutation rate.

Firstly, the integrity of replication will be relatively impaired and the variant will exhibit an increased mutation rate.

First, an increased mutation rate should lead to a simple increase in the rate at which cheating mutations are generated.

An increased mutation rate following deletion of mismatch repair genes has been demonstrated both in Bacteria and Eukarya.

The presence of readily melting DNA correlates with a higher AT content compared to the genome average and suggests that this region may be less thermodynamically stable and likely subject to an increased mutation rate [37].

We determine the circumstances that select for an increased mutation rate and the circumstances when an increased mutation rate accelerates tumour progression.

We found evidence of increased mutation rate in species with more intense sexual selection.

Hypermethylated subgroups in colon and endometrial cancer were associated with MLH1 inactivation and increased mutation rate.

An increased mutation rate after integration could also have contributed to sequence diversity in this region.