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This requires either significantly increased costs from denser sensor deployment in the case of global simultaneous/parallel measurements, or increased measurement time and labor in the case of global sequential measurements.
Although it is possible to use off-line high-performance liquid chromatography (HPLC) separation before MALDI-MS measurement, this solution has some disadvantages, mainly the significantly increased measurement time needed to analyse a sample.
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The rafts were created such that the epidermis did not completely overlap the dermis, thereby allowing spectral measurement of the two strata without need for a confocal setup and increased measurement times.
In contrast to random errors with a constant variance, the Fisher information can decrease for unknown systematic errors and, thus, the Cramér-Rao bound can increase with an increasing measurement time.
This drift increased significantly with increasing measurement time, thus preventing accurate measurements of long-term pHe changes in the tumours.
For specific applications the use of (additional) high resolution H NMR spectra could further enhance sensitivity as well as accuracy [ 31], but thereby increase measurement time.
Sensitivity can be further enhanced by increasing the measurement time.
The impedance from a degraded square waveform generated by a cost-effective power controller was able to be determined by increasing the measurement time, which aided averaging.
Also, the acquisition of the WAXS data from the same sample does not significantly increase the measurement time, but it provides additional data of the composition and crystal structure and size of the sample.
Distributed Space Missions such as formation flight and constellations, are being recognized as important Earth Observation solutions to increase measurement samples over space and time.
Attempts to increase measurement sensitivity and shorten incubation times by reducing the headspace thickness to 1 2 cm generally cause denitrification to be underestimated by 3 13% for gas headspaces, and up to 80% for water headspaces.
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