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Unexpectedly, LD tests provided only weak evidence of increased linkage, with a single significant test for a locus pair at dhfr double mutants and another for dhps single mutants.
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Trade-related infrastructures allow increased linkages with the global supply chain to reach trading partners for both intra-trade and extra-trade.
In the subsequent five-year period, there was increasing linkage with other policy areas including development, health, and climate change through the Global Platforms in 2011 and 2013 (WHO 2013).
The comment " increase linkages with the health sector" (#17 South Asia) is representative, as is " the organisation... needs to continue its catalyst role in strengthening and extending services... of the state in district and rural areas" (#20 South Asia).
One approach to increase the power in linkage and association studies is to study small populations with increased linkage disequilibrium and decreased genetic diversity.
We find that Type I error increases gradually with increased linkage.
What are the implications of increased linkages?
Increasing linkage of such datasets and additional linkages with population health registries, such as cancer, stroke, coronary heart disease and pharmaceuticals [ 31- 34], will increase the need for assessments of the usefulness and accuracy of the linked data.
The Hawkesbury campus of Western Sydney University has an established water recycling scheme to support both agricultural productivity and landscape amenity, along with increasing linkages to infrastructure protection from bush fire risk.
Ukraine's increased economic linkages with China began long before the 2014 Russian annexation of Crimea.
"Looking ahead, financial stability risks could rise if retail participation significantly increased or linkages with the formal financial sector grew without material improvements in market integrity, anti-money laundering standards and cyber defences," Carney noted.
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