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Significant and clinically meaningful improvements, low NNTs and increased likelihood of achieving longer term outcomes with an earlier PRO response indicate that CZP is an effective treatment option, offering substantial benefits to patients.
Those not tested had a similar risk of viral rebound and treatment switch to HLA B∗5701 negatives, but a slightly increased likelihood of achieving an undetectable viral load (hazard ratio = 1.15, 95% CI 1.06 1.24).
With 52 weeks of ExQW, patients experienced sustained improvements in glycaemic control and CV risk factors, with an increased likelihood of achieving both a clinically relevant composite outcome (HbA1c < 7% without weight gain or increased risk of hypoglycaemia) and a composite of key therapeutic goals (HbA1c < 7%, BP < 130/80 mm Hg, LDL < 100 mg/dl).
The same four factors were associated with an increased likelihood of achieving a ≥50 % reduction in seizure frequency [ 84].
The increased likelihood of achieving viral suppression among ZDV-experienced women may be due to better treatment adherence or frequency of viral load monitoring.
This study demonstrates that providing patients with a larger statin fill size is associated with greater adherence as well as an increased likelihood of achieving lower cholesterol levels.
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For fewer crosses to succeed an increased likelihood of success of each cross has to be achieved by making greater efforts than normal to choose complementary parents.
ExQW also increased the likelihood of achieving a clinically relevant composite outcome of an HbA1c < 7% without weight gain or increased risk of major/minor hypoglycaemia, as well as the composite ADA goals of HbA1c < 7%, SBP/DBP < 130/80 mm Hg and LDL < 100 mg/dl.
Advances in surgery have increased the likelihood of achieving local disease control and now limited distant spread may also be considered for resection.
Each kilogram of weight loss increased the likelihood of achieving a remission 1.2 times.
Delaying intervention increased the likelihood of achieving immediate patency (OR 0.55, 95% CI 0.31 1.0, P = 0.05).
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