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On the other hand, untreated cirrhotic animals (CI) showed an increased Kt (p < 0.01) compared to controls, expressing a lower affinity of transporters for their substrates.
In more advanced cirrhosis the atrophy of the mucosa may in addition lead to a reduction in carrier number, explaining the reductions of maximal velocity (Vmax) and affinity of the transporters for their substrates (expressed as increased Kt) (Table 2).
Kinetic studies showed a decreased Vmax and a reduced affinity for sugar and four amino acids transporters (expressed as an increased Kt) in the brush border membrane vesicles from untreated cirrhotic rats as compared with controls.
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As normally observed, the fatigue strengths of both the untreated and carburized specimens decreased with increasing Kt.
All carburized notched specimens showed higher fatigue strength than the untreated ones, and the extent of increase in fatigue strength decreased with increasing Kt and then saturated at high Kt values.
Based on our results, we calculated required time and dialysate to increase Kt with different Qd using calculated Kmin (Table 2).
It is probable that a GnRH-related cue is responsible for the increased 11-KT and decreased E2 levels detected in the gonads of black molly masculinized individuals.
Under this hypothesis, it is the efficiency, not the strength, of selection that would increase post-KT as the reduced power of genetic drift would have improved the ability of natural selection to eliminate aggressive mobile elements and other mildly deleterious insertions.
In contrast, KD1L17R-KT increased the fibrinolysis midpoint to 27 min at 2 μM, to 37 min at 3 μM, and to >60 min at 5 μM, respectively.
Because the active-site inhibition of plasmin by both KD1L17R-VT and KD1L17R-KT is similar, the additional increased potency of KD1L17R-KT could be due to its binding to the kringle domains of tPA and/or plasminogen.
The estimated value of whole plant hydraulic conductance (KT) confirmed increased hydraulic and stomatal resistance under deficit irrigation condition while well-watered pepper plants had greater water uptake rate and remarkably higher within plant (hydraulic) and stomatal conductance.
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