Depression, the number of daily pills, and the pill burden were associated with increased irregularity, and euthymia was associated with regularity.
As the number of TACE procedures increased (median 3.5, range 1 10), these patients presented with increasing irregularities and narrowing of vessel walls, or even occlusions.
This conclusion is also somewhat in contrast to other studies that have found increased irregularity of velocity-controlled and constrained motion paths in chronic WAD compared with healthy participants [ 54, 55].
For Cases 1 and 2, increasing psychotic symptoms within an episode translated into reduced mean activity levels (case 1), greater variation between rest and activity, and periods with distinctly increased irregularity in activity (sample entropy).
Of note, there was increased irregularity in the RPE; the IS/OS junction and the ELM could no longer be visualized.
However, as PCs fire highly regularly in slice preparations in which their synaptic inputs are blocked [17], [18] and since they show increased irregularity following mutations of their voltage gated Ca2+ channels [13], the endogenous properties of PCs are likely to contribute to their regularity of firing.
The total number of psychotropic drugs, pill burden and depression were associated with increased irregularity.
Medication regimen complexity and depressed mood are associated with increased irregularity.
Both the total number of psychotropic medications and the pill burden were associated with increased irregularity.
In this study, depression, the pill burden, and total number of psychotropic medications were associated with increased irregularity in daily antidepressant dosage, while euthymia was associated with increased regularity.
