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GluA1-RC levels in the membrane were increased in acquisition, consolidation and retrieval phases; GluA2-RC and GluA3-RC membrane levels were reduced and modulated in early endosomes during these phases.
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On the contrary, T/B ratios for the focal 99mTc- V DMSA uptake in invasive tumors were not significantly increased in the late acquisitions (mean ± SD, 1.76 ± 0.28 at 10 min versus 1.99mTc- V DMSA60 min; P > 0.05).
dynamic angio Coronal 5 mm Breath-hold Yes Acquisition in shallow free breathing possible (no increase in acquisition time) X X 3D gradient echo T1-w.
4-6 mm Breath-hold No Triggered acquisition in free breathing (5 min increase in acquisition time) X (X) (X) Fast spin echo T2-w.
However, increasing the administered activity has been shown to be less effective at improving image quality than the same proportional increase in acquisition time [5].
Moreover, it might be possible to place the aperture before the specimen, which would give a decrease in dose and an increase in acquisition rate.
or IR) 4-6 mm Breath-hold No Triggered acquisition in free breathing (5 min increase in acquisition time) X (X) Diffusion weighted imaging Multi breath-hold No Triggered acquisition in free breathing (5 min. increase in acquisition time) X X 3D gradient echo T1-w.
Figure 3 illustrates why increasing the administered activity is less effective at improving image quality than the same proportional increase in acquisition time, particularly for heavier patients for whom the NECR may already be approaching its peak value.
The use of additional SPECT/CT for evaluating suspicious or equivocal lesions observed on WB-BS has been shown to improve diagnostic confidence [4, 7, 8, 10], but the resulting increase in acquisition time is undesirable.
Transverse 4 mm (interpolated) Breath-hold no Not available/to be developed X X X Fastspinpin echo T2-w., half Fourier Coronal 6-8 mm Breath-hold No Triggered or non triggered acquisition in free breathing (0-5 mincreasease in acquisition time) X X X X Steady state GRE Coronal 4-6 mm Free breathing No No change needed X X X Fastspinpin echo T2-w., rotating phase encoding Coronal (non-fat sat).
This saving offsets the increase in acquisition and consumables costs with Aprokam (Fig. 1).
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