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The superiority of the GE_ref over the BL_ref scheme would therefore have increased further over time.
The effect was detectable as early as 12 hours following stimulation of the cells and increased further over time to reach a plateau at 48 hours.
Both SNAP25 and synaptophysin immunoreactivity were already elevated compared with controls at 4 months of age, and levels of both proteins subsequently increased further over time (Fig. 6B and data not shown).
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Ferritin levels were increased in AI compared to the reference value and also hepcidin, and IL-6 levels were high, but did not increase further over time (Fig. 2).
The research project is designed to include a minimum of 250 patients; however, all patients treated at the unit are invited to participate, so the sample size is expected to increase further over time.
The authors also demonstrated that sELAM-1 decreased over time in septic patients while sICAM-1 increased further [ 11].
Haptoglobin levels were increased at admission compared to reference values and further increased over time (Fig. 2).
In contrast, postoperative controls already showed increased levels of oxidative stress prior to surgery (P/T0), which further increased over time after the surgical procedure (P/T1, P/T2).
A striking result not reported by previous research was the high initial self-reported self-esteem in our sample, which further increased over time.
Some CpGs were initially unmethylated (M value below −1) and became methylated (M value above 1) while other CpGs had M values above 1 that further increased over time.
Some differences have increased over time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com