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As noted above, NOX-induced ROS contribute to increasing calcium release from SR. Reid [38,39] showed that reduction of ROS below basal levels reduced the force production of skeletal muscle, while increasing ROS to a certain point increased force production, and ROS exposure above that point resulted in a reduction in force production [40].
There was an increase in the mass of all skeletal muscles examined and both the soleus and EDL exhibited increased force production.
Arginine supplementation by DMD patients stems from reports that short-term, arginine treatment for 2 6 weeks has beneficial effects in young, mdx mice that include increased utrophin expression, increased force production, decreased inflammation and decreased fiber damage [31] [34].
Both factors may have increased force production and contraction speed of the biceps, thereby improving AC performance.
Viewing emotional as compared with neutral images led to increased force production and increased blood oxygen level dependent (BOLD) activity in human ventrolateral PFC (vlPFC) (Schmidt et al. 2009).
The unchanged levels of peak and resting [Ca2+]i coupled with the slower kinetics of the Ca2+ transient cannot explain the depressed cardiac contractility in diabetic rats [ 32], since these alterations would favour increased force production, which was not observed here.
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These results support the high strength and power demand of RA in soccer and suggest that the hypertrophy of RA muscle could play an important role when training to increase force production during kicking.
Different muscles use different strategies to increase force production.
The MUmV reflects the property that a motor unit increases force production as the firing rate increases to a point where further increases in firing rate have no effect.
Interestingly, recent results show that cells can increase force production in response to a stiffer environment [ 13] and that cells are actively mechanoresponsive [ 33], suggesting that an external mechanical cue may be sufficient to initiate net contraction.
In hatchlings exhibiting monophasic force production, increasing force was applied during the middle of the downstroke phase (Figs 3, 5).
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