It remains to be investigated whether the higher positive scores in patients from "at risk for psychiatric disorder" families are indicative of an increased familial loading for psychosis or whether these higher scores lead to higher psychosis dimension scores in the relatives.
Finally, we calculated breast cancer mortality risk (hazard ratio, HR) for patients with a highly increased familial risk compared to those without a family history, adjusting for all other factors significantly linked to survival.
Use of family members as interpreters who themselves may be at increased familial cancer risk was also stressful for people and no less problematic.
We excluded patients with a moderately increased familial risk in order to maximise the difference in effect of family history.
Twin studies concur with this increased familial liability.
The increased familial risk of cluster headache strongly suggests a genetic cause.
An increased familial risk can be caused by genetic as well as environmental factors.
Dove-Edwin et al. calculated mortality risk reduction up to 80% by identifying and subsequently screening individuals with an increased familial colorectal cancer (CRC) risk[5].
The significantly increased familial risk for CH, drug overuse and substance abuse suggests that genetic factors are involved in the process of headache chronification.
The aim of the present study was to examine whether related neural abnormalities might be present in young people at increased familial risk of depression but with no personal history of illness.
As we were interested in examining both sub-syndromal and syndromal mood disorder symptoms, we also included those participants who did not meet formal RDC criteria for a mood disorder but who may still be at greater risk of developing symptomatology due to increased familial risk.
